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TB-500

10mg Vial
2 July 2026Updated 27 August 2026
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Full range of benefits for TB-500

May promote cell migration via actin cytoskeleton remodeling

Associated with enhanced angiogenesis and blood vessel formation in models

May accelerate wound epithelialization and granulation tissue formation

Shown to modulate inflammation and reduce pro-inflammatory cytokines in studies

May reduce fibrosis and scar formation by influencing extracellular matrix remodeling

Associated with increased expression of matrix metalloproteinases to aid tissue remodeling

Shown to support tendon and muscle repair in animal injury models

May have cardioprotective effects in preclinical myocardial injury models

Reported to promote corneal and ocular surface healing in research models

May enhance neuroprotection and axon outgrowth in some preclinical studies

This peptide's combination-safety and interaction data below always stays visible, regardless of membership.

Warning

Important information. The data compiled from scientific literature is provided for educational purposes. Dosage ranges reflect what is reported in studies and do not constitute a recommendation, prescription, or usage guidance. Health decisions should always be made with a qualified professional.

Peptide Interactions

// 12 known interactions

Works exceptionally well with this peptide

Platelet-rich plasma (PRP)

Local application or injection of PRP supplies concentrated growth factors and matrix signals that can act additively with TB-500's promotion of cell migration and angiogenesis to enhance soft-tissue repair.

BPC-157

This regenerative peptide has complementary pro-healing and angiogenic effects, and co-administration may produce additive benefits in tissue repair pathways.

Vitamin C (ascorbic acid)

As an essential cofactor for collagen synthesis and extracellular matrix formation, vitamin C can support TB-500–mediated tissue remodeling and wound healing.

All interaction categories

Synergistic (3)

  • Platelet-rich plasma (PRP): Local application or injection of PRP supplies concentrated growth factors and matrix signals that can act additively with TB-500's promotion of cell migration and angiogenesis to enhance soft-tissue repair.
  • BPC-157: This regenerative peptide has complementary pro-healing and angiogenic effects, and co-administration may produce additive benefits in tissue repair pathways.
  • Vitamin C (ascorbic acid): As an essential cofactor for collagen synthesis and extracellular matrix formation, vitamin C can support TB-500–mediated tissue remodeling and wound healing.

Compatible (3)

  • Acetaminophen (paracetamol): Analgesic effect is achieved via central mechanisms with no known interaction with TB-500 or its regenerative actions, making it a generally neutral co-treatment for pain control.
  • Topical antiseptics (chlorhexidine, povidone-iodine): Local antiseptics used for infection control have primarily topical activity and no established systemic interaction with TB-500.
  • Multivitamin/mineral supplements: Routine nutritional supplementation provides general support for healing processes and has no specific pharmacologic interaction with TB-500.

Monitor (3)

  • Anticoagulants (warfarin, DOACs): Because TB-500 influences tissue remodeling and angiogenesis, monitor bleeding signs and coagulation parameters (e.g., INR) when combined with anticoagulants.
  • Systemic corticosteroids: Corticosteroids impair inflammation and wound repair and may reduce the clinical effectiveness of TB-500, so monitor healing outcomes and consider dose/timing adjustments.
  • Immunosuppressive therapies (methotrexate, biologic TNF inhibitors): Immunosuppression can alter infection risk and regenerative responses, therefore monitor wound healing, infection markers, and overall therapeutic response when used with TB-500.

Avoid (3)

  • Active malignancy or recent cancer history: Because TB-500 promotes cell migration and angiogenesis, evaluate the risk–benefit carefully and avoid or use only under oncology guidance due to theoretical pro-tumorigenic concerns.
  • Pregnancy and breastfeeding: Safety data are lacking for use in pregnancy and lactation, so avoid unless specialist review indicates potential benefit outweighs unknown risks.
  • Concurrent growth hormone or IGF-1 therapy: Co-administration with other anabolic/proliferative agents may produce overlapping proliferative effects and require specialist assessment for increased adverse proliferative risk.