Abstract analysed
The effect of tripeptide-copper complex on human hair growth in vitro.
In ex vivo human hair follicles and cultured human dermal papilla cells, AHK-Cu (10^-12 to 10^-9 M) stimulated follicle elongation and DPC proliferation and altered apoptosis-related proteins (increased Bcl-2/Bax, decreased cleaved caspase-3 and PARP), though a direct apoptosis assay showed a non-significant reduction in apoptotic cells; results are preclinical and limited by incomplete reporting in the abstract.
Confirmatory studies with reported sample sizes, replicates, and statistical analyses on human follicles and DPCs.Mechanistic studies linking molecular anti-apoptotic changes to functional outcomes in follicles.In vivo studies (animal models) and ultimately controlled human clinical trials to assess efficacy and safety.+2 more
Relevance
100%
Published
2007